Case studies

A private research organization focused on evaluating the safety and effectiveness of medications. Their goal is to use advanced data analysis to support healthcare decisions and meet regulatory standards. For this project, they aimed to assess the safety of hydroxychloroquine, used alone or with azithromycin, for treating rheumatoid arthritis. The study focused on identifying short-term side effects and long-term risks, especially related to heart health and the use of multiple medications together. The client needed a data-driven approach to fill gaps in existing evidence by combining different clinical data sources, identifying patient groups with similar characteristics, and addressing factors that could affect treatment outcomes.

Large data volumes are revolutionizing industries, including medical research. This influx of data enables observational studies that harness global statistical evidence. However, conducting such studies can be labor-intensive and prone to inconsistencies due to disconnected communication channels, like repositories, emails, forums, and chats. Moreover, adapting code to different environments during the execution phase can create unscalable and non-reusable analytical frameworks. In response, the OHDSI community is developing ARACHNE, an innovative platform designed to streamline observational research by fostering collaboration among life sciences, healthcare, academia, and organizations handling patient-level data.

The OMOP CDM is widely recognized as the industry standard for observational health research. It provides a standardized data model that facilitates data integration and sharing across different sources, enabling researchers to conduct studies at scale. ATLAS is a central tool used for research within the OMOP CDM ecosystem, providing a user-friendly interface for querying the data model and creating visualizations. Building well-defined cohorts is a critical first step in conducting research using the OMOP CDM. By selecting and defining cohorts of patients with specific characteristics or conditions, researchers can ensure that their studies are focused and relevant, and can generate reliable evidence.

We have extensive experience in automating mappings between medical coding and classification systems by computationally processing their semantic meaning, which can be extracted using NLP methodology or explicitly available from the classification model. Our successful applications include mappings made from ICD-10-PCS, LOINC, and ICD-O-3 systems for OHDSI OMOP Standardized Vocabularies.

We teamed up with a Swiss agri-tech startup to build a platform that uses satellite images, radar data, and machine learning to give farmers a clear view of their crops. The system helps predict crop yields, spot weeds early, and estimate sugar content, giving farmers the info they need to boost their harvests and run their farms more efficiently.

Our client, a technology company managing large data centers, faced recurring pump failures in their cooling systems, causing costly downtimes. By deploying an advanced anomaly detection system, we identified critical sensor patterns that allowed the maintenance team to address issues before they escalated. This led to a 30% reduction in false alarms and a 25% decrease in unplanned downtime.

A web application designed to facilitate communication in psychopathology treatment by summarizing mental health test results and illustrating treatment dynamics.

Jackalope transforms complex medical data into OMOP CDM and SNOMED Clinical Terms (CT) standardized formats. This enables healthcare providers, practitioners, and scientists to effectively use real-world medical data for research and delivering enhanced patient care.